Beneficial Effects of Electric Cell Signaling on Urogenital Conditions in Women

Electric cell signaling treatment (EcST), often referred to as bioelectronic medicine, involves the use of specific-parameter energy frequencies to modulate bodily functions and treat various medical conditions. This technology has shown promise in addressing urogenital conditions in women, such as overactive bladder, interstitial cystitis, chronic pelvic pain, and sexual dysfunction. Below is a detailed scientific description of the potential benefits of electric cell signaling treatment (EcST) for these conditions, supported by references.

Mechanisms of Electric Cell Signaling

1. Neuromodulation: Electric cell signaling can modulate the activity of nerves that control urogenital functions. By targeting specific neural pathways, it can alter the transmission of nerve impulses, which can help in reducing symptoms of various conditions.
2. Muscle Stimulation: Electric cell signaling treatment (neoGEN®} can directly influence the muscles of the pelvic floor and bladder. This can help in strengthening these muscles, improving bladder control, and reducing symptoms of urinary incontinence.
3. Anti-inflammatory Effects: Electric cell signaling (EcST) has been shown to have anti-inflammatory effects, which can be beneficial in conditions like interstitial cystitis, where inflammation of the bladder lining is a primary symptom.
4. Pain Modulation: Electric cell signaling treatment (neoGEN®} can activate endogenous pain control pathways, providing relief from chronic pelvic pain and other pain-related urogenital conditions.

Potential Benefits for Urogenital Conditions

1. Overactive Bladder (OAB)
   • Mechanism: Electric energy stimulation of the sacral nerves (sacral neuromodulation) can reduce involuntary bladder contractions.
   • Benefits: Studies have shown that sacral neuromodulation can significantly improve symptoms of OAB, including urinary frequency, urgency, and incontinence.

2. Interstitial Cystitis (IC)

1. • Mechanism: Electric cell signaling (EcST) can reduce bladder inflammation and modulate pain pathways.
   • Benefits: Clinical trials have demonstrated that electric energy stimulation can reduce pain and urinary symptoms in patients with IC .

3. Chronic Pelvic Pain

1. • Mechanism: Electric energy stimulation can activate descending pain inhibitory pathways and reduce central sensitization.
   • Benefits: Patients with chronic pelvic pain have reported significant pain relief and improved quality of life with electric cell signaling treatment.

4. Urinary Incontinence

1. • Mechanism: Electric stimulation (neoGEN®) can strengthen pelvic floor muscles and enhance bladder control.
   • Benefits: Pelvic floor electric energy stimulation has been effective in reducing stress urinary incontinence and mixed urinary incontinence symptoms in women .

5. Sexual Dysfunction

1. • Mechanism: Electric signal stimulation can improve blood flow and nerve function in the pelvic region.
   • Benefits: Some studies have indicated that electric cell signaling treatment can improve sexual arousal and reduce pain during intercourse for women with sexual dysfunction.

References

1. Sievert, K. D., et al. (2010). “Sacral Neuromodulation for Lower Urinary Tract Dysfunction: A Review of the Literature and Current Practice.” Therapeutic Advances in Urology, 2(3), 139-153.
2. Kessler, T. M., et al. (2010). “Sacral Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: Systematic Review and Meta-Analysis.” European Urology, 58(6), 865-874.
3. Marcelissen, T. A. T., et al. (2011). “Neuromodulation in Chronic Pelvic Pain Syndromes.” International Urogynecology Journal, 22(9), 1125-1130.
4. Bosch, P. C., et al. (2013). “Interstitial Cystitis/Bladder Pain Syndrome and Associated Disorders.” Campbell-Walsh Urology. Elsevier, 415-420.
5. Gilling, P. J., et al. (2010). “Electrical Stimulation for the Treatment of Chronic Pelvic Pain Syndrome in Men: A Pilot Study.” BJU International, 105(1), 31-34.
6. Castro, R. A., et al. (2008). “Effect of Pelvic Floor Muscle Training and Electrical Stimulation in the Treatment of Female Urinary Incontinence: A Randomized Controlled Trial.” International Urogynecology Journal, 19(12), 177-182.
7. Dumoulin, C., et al. (2010). “Pelvic Floor Muscle Training Versus No Treatment, or Inactive Control Treatments, for Urinary Incontinence in Women: A Short Version Cochrane Review.” Neurourology and Urodynamics, 29(5), 783-790.
8. Meston, C. M., et al. (2005). “A Review of the Hypothetical Role of the Autonomic Nervous System in Female Sexual Arousal.” Journal of Sexual Medicine, 2(2), 124-144.

In conclusion, electric cell signaling treatment (EcST) offers a promising non-invasive therapeutic approach for various urogenital conditions in women, leveraging mechanisms like neuromodulation, muscle stimulation, anti-inflammatory effects, and pain modulation. Further research and clinical trials will continue to refine and expand the applications of this innovative technology (neoGEN® by RST-Sanexas, Inc).